ABSTRACT Phase variation occurs in many pathogenic and commensal bacteria and is a major generator of genetic variability.A putative advantage of phase variation is to counter reductions in variability imposed by nonselective bottlenecks during transmission.Genomes of Campylobacter jejuni, a widespread food-borne pathogen, contain multiple phase-va
Skeletal muscle conveys the Water Filter Package beneficial effects of physical exercise but due to its heterogeneity, studying the effects of exercise on muscle fibres is challenging.Here, the authors carry out proteomic analysis of myofibres from freeze-dried muscle biopsies, show fibre-type specific changes in response to exercise, and show that
BackgroundSuicide rates are higher in rural Australia than in major cities, although the factors contributing to this are not well understood.This study highlights trends in suicide and examines the prevalence of mental health problems and service utilisation of non-Indigenous Australians by geographic remoteness in rural Australia.MethodsA retrosp
We have previously identified and characterized the phenomenon of ectopic Pinch Bowl human centromeres, known as neocentromeres.Human neocentromeres form epigenetically at euchromatic chromosomal sites and are structurally and functionally similar to normal human centromeres.Recent studies have indicated that neocentromere formation provides a majo
During malting, production of enzymes is activated in barley grain; these enzymes degrade storage substances that are subsequently used in germination.During kilning, malt phosphatases release inorganic phosphases from phytates to wort, phosphases contribute to maintaining the optimum pH for most of the malt enzymes.During fermentation, phosphates